×

Activity Feed

Dmitrii Kriukov @shappiron
> Mathematical Physics for Aging Discovery : I do not see here a concrete plan of the project, it sounds like “let’s take some big data and train some complex dynamical model!”. I believe you need to describe your analysis steps in more detailed manner to ask for funding. Otherwise, the risk of failure is extremely high.
5 months ago
Dmitrii Kriukov @shappiron
> Mathematical Physics for Aging Discovery : Using transcriptomes as feeded data is a barely good idea - they are rather noisy and preprocessing step is tough. You need to describe your method for preprocessing or, at least, give a reference where such a method was given.
5 months ago
Dmitrii Kriukov @shappiron
> Mathematical Physics for Aging Discovery : “analysis of matrix eigenvalues can give us a representation of GRN structure (clustering, existence of cliques, hubsn and other patterns)” - eigenvalues is obviously not * enough for all these procedures, at least you need eigenvectors here.
5 months ago
Dmitrii Kriukov @shappiron
> Mathematical Physics for Aging Discovery : In general, you use linear system of equations, why do you assume this assumption will work well?
5 months ago
Dmitrii Kriukov @shappiron
> Mathematical Physics for Aging Discovery : There is a mistake in equation 1 description: you use stochastic equation - not deterministic. And there is no reference for such an equation approving its siutability.
5 months ago
More